Chernavskii D S, Palamarchuk E K, Polezhaev A A, Solyanik G I, Burlakova E B
Biosystems. 1977 Dec;9(4):187-93. doi: 10.1016/0303-2647(77)90002-8.
A mathematical model of the regulation of the cell cycle by the plasma membrane is suggested. The model is based on the hypothesis that structural transitions of the cell membrane play an important role in the regulation of cell division. Conditions of transition from the proliferating state to the resting state and back are investigated. Possible qualitative differences between models of the cell cycle of a normal and a tumour cell are pointed out.
提出了一种关于质膜对细胞周期调控的数学模型。该模型基于这样的假设：细胞膜的结构转变在细胞分裂调控中起重要作用。研究了从增殖状态转变为静止状态以及再转变回增殖状态的条件。指出了正常细胞和肿瘤细胞的细胞周期模型之间可能存在的质的差异。
