Lancourt J E, Hochberg F
Clin Orthop Relat Res. 1977 May(124):214-8.
The incidence of fractures in primary hyperparathyroidism is highly variable. The possibility that there might be an increased susceptibility to fracture is discussed. Healing in most is without delay. Three cases of delayed or nonunion following fracture are presented. In all three, healing accelerated dramatically after excision of a parathyroid adenoma. A pathological fracture secondary to the hyperparathyroidism of parathyroid carcinoma healed after excision of the tumor allowed regression of the osseous lesions. The endocrinologic mechanisms which cause nonunion in a small percentage of cases have not been clearly elucidated.
原发性甲状旁腺功能亢进症骨折的发生率差异很大。本文探讨了骨折易感性增加的可能性。多数情况下骨折愈合并无延迟。本文报告了3例骨折后延迟愈合或不愈合的病例。在所有这3例中，切除甲状旁腺腺瘤后愈合明显加快。甲状旁腺癌所致甲状旁腺功能亢进继发的病理性骨折，在切除肿瘤使骨病变消退后愈合。少数病例中导致骨折不愈合的内分泌机制尚未完全阐明。
