O'Brien J P
Clin Orthop Relat Res. 1977 Oct(128):56-64.
Infections of the spine usually involve the vertebral body and therefore by definition produce a kyphosis. Non-tuberculous infection usually staphylococcal and in the lumbar spine, is often diagnosed late and can involve the cord. Open exploration and stabilization with graft should therefore be considered. The destruction is usually less extensive and therefore the kyphosis less severe than in late neglected tuberculous infections. Tuberculous spinal infection accounts for 59% of all orthopedic tuberculosis. It invariably involves vertebral bodies and is progressive. Destruction of the bodies is by infection and avascular necrosis, kyphosis is inevitable and cord compression a common threat. While L-1 is the most commonly affected body T-10 is statistically the most commonly associated with cord compression. The treatment of spinal tuberculosis should be aimed at correcting 5 basic defects associated with the disease and the deformity: mechanical instability; chronic smoldering infection; spinal cord and nerve root compression; disturbance of spinal growth; depressed lung function. The cornerstone to effective treatment for spinal tuberculosis is drug therapy and the anterior fusion operation. For the established tuberculous kyphosis, which is always a fixed deformity, multiple staged operations and gradual correction used the Halo-pelvic apparatus is the best treatment available at present.
脊柱感染通常累及椎体,因此根据定义会导致脊柱后凸。非结核性感染通常为葡萄球菌感染,好发于腰椎,常诊断较晚,且可累及脊髓。因此应考虑进行开放探查及植骨固定。与晚期未治疗的结核性感染相比,其破坏通常范围较小,脊柱后凸也较轻。脊柱结核占所有骨科结核的59%。它总是累及椎体且呈进行性发展。椎体破坏是由感染和缺血性坏死引起的,脊柱后凸不可避免,脊髓受压也很常见。虽然L1是最常受累的椎体,但从统计学角度来看,T10最常与脊髓受压相关。脊柱结核的治疗应旨在纠正与该疾病及畸形相关的5个基本缺陷:机械性不稳定;慢性隐匿性感染;脊髓和神经根受压;脊柱生长障碍;肺功能下降。脊柱结核有效治疗的基石是药物治疗和前路融合手术。对于已形成的结核性脊柱后凸,这始终是一种固定畸形,目前最好的治疗方法是采用头环骨盆装置进行多阶段手术及逐步矫正。