Korot'ko G F, Sukhoterin V G
Fiziol Zh SSSR Im I M Sechenova. 1977 Dec;63(12):1697-703.
In chronic experiments on dogs, i. v. administration of trypsinogen (5 mg) raised enzyme--secreting activity of the gastric glands. An increase in pepsinogen secretion by the gastric glands was noted also in acute experiments early after ligation of pancreatic ducts when tryptic activity of the blood was rising. The activating effect of trypsinogen was also revealed on the rat stomach in vitro.
在对狗进行的慢性实验中,静脉注射胰蛋白酶原(5毫克)可提高胃腺的酶分泌活性。在急性实验中,当血液中的胰蛋白酶活性升高时,在结扎胰管后的早期也观察到胃腺的胃蛋白酶原分泌增加。胰蛋白酶原对大鼠胃的激活作用在体外也得到了证实。