Enat R, Barzilai D
Isr J Med Sci. 1977 Dec;13(12):1197-205.
Electron microscopy study of a liver biopsy from a patient with the Dubin-Johnson syndrome revealed evidence of severe mitochondrial damage. The changes included membranous whorls, isolated intramitochondrial membranes, myelin figures and large cytoplasmic vacuoles, presumably representing degenerated micochondria. Mitochondrial damage should be looked for in future electron microscopy studies in patients with the Dubin-Johnson syndrome.
对一名患有杜宾-约翰逊综合征患者的肝脏活检组织进行电子显微镜研究，发现了严重线粒体损伤的证据。这些变化包括膜性涡旋、孤立的线粒体内膜、髓鞘样结构和大的细胞质空泡，推测代表退化的线粒体。在未来对杜宾-约翰逊综合征患者进行的电子显微镜研究中应留意线粒体损伤情况。
