Leshchinskiĭ L A, Trusov V V
Kardiologiia. 1977 Nov;17(11):125-32.
Central and regional hemodynamics was studied in 228 patients with acute myocardial infarction by a complex of radio-indication tests. It was established that the degree of changes in central hemodynamics correlates to a definite extent with the severity of myocardial involvement (size of the damaged zone). Regional hemodynamics did not always change parallel to the reduction in cardiac output. The character of circulation in the organs of patients with myocardial infarction depends greatly on the internal control factors and the degree of tonic tension of the regional vessels. Changes in the regional circulation in myocardial infarction lead to hypoxia of the organ and severe disturbances in its function. In most patients the intraorganic hemodynamics decrease gradient was 11/2-2 times more than the cardiac output reduction gradient. Hemodynamic changes in myocardial infarction at the level of different vessels are of a multicomponent and non-linear character. The extent and rate of restoration of intra-organic hemodynamics are greatly determined by the severity of myocardial infraction and the presence of complications.
通过一系列放射性指示试验，对228例急性心肌梗死患者的中心和区域血流动力学进行了研究。结果表明，中心血流动力学的变化程度在一定程度上与心肌受累的严重程度（受损区域大小）相关。区域血流动力学并不总是与心输出量的降低平行变化。心肌梗死患者器官内的循环特征在很大程度上取决于内部控制因素和区域血管的紧张度。心肌梗死时区域循环的变化会导致器官缺氧及其功能的严重紊乱。在大多数患者中，器官内血流动力学降低梯度比心输出量降低梯度大1.5至2倍。不同血管水平的心肌梗死血流动力学变化具有多成分和非线性特征。器官内血流动力学恢复的程度和速度在很大程度上取决于心肌梗死的严重程度和并发症的存在。
