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继发性甲状旁腺功能亢进中的甲状旁腺自体移植(作者译)

[Parathyreoid autoransplantation in secondary hyperparathyreoidism (author's transl)].

作者信息

Klempa I

出版信息

Langenbecks Arch Chir. 1977 Dec 14;344(3):171-8. doi: 10.1007/BF01254071.

DOI:10.1007/BF01254071
PMID:599990
Abstract

Subtotal Parathyreoidectomy offers no problem after surgery, nor after Kidney transplantation. But a recurrence needs extensive investigations for localisation of recurrent hyperplastic glands. The necessary reoperation is loaded with difficulties. After total Parathyreoidectomy hypocalcaemia is a severe complication. Therefore in patients awaiting Kidney transplants in a chronic dialysis program the procedure is not opportune. In 11 patients following total Parathyreoidectomy and autoplastic parathyreoid transplant, we found nearly normal parathyreoid hormone plasma levels. The advantage of this method is: The function of the autoplastic graft is testable and a possible recurrence is easily resectable.

摘要

次全甲状旁腺切除术在术后以及肾移植后均无问题。但复发时需要进行广泛检查以定位复发的增生性腺体。必要的再次手术困难重重。全甲状旁腺切除术后低钙血症是一种严重并发症。因此,对于正在接受慢性透析治疗且等待肾移植的患者,该手术并不适宜。在11例行全甲状旁腺切除及自体甲状旁腺移植的患者中,我们发现血浆甲状旁腺激素水平接近正常。该方法的优点是:自体移植的功能可检测,且可能的复发易于切除。

相似文献

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Langenbecks Arch Chir. 1977 Dec 14;344(3):171-8. doi: 10.1007/BF01254071.
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本文引用的文献

1
AUTO- AND ISOTRANSPLANTATION, IN DOGS, OF THE PARATHYROID GLANDULES.狗甲状旁腺自动和同种移植。
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2
AUTONOMOUS SECONDARY (RENAL) PARATHYROID HYPERPLASIA.自主性继发性(肾性)甲状旁腺增生
N Engl J Med. 1964 Dec 24;271:1342-5. doi: 10.1056/NEJM196412242712604.
3
Parathyroid transplants in rats; a comparison of their survival time with that of skin grafts.大鼠甲状旁腺移植;其存活时间与皮肤移植存活时间的比较。
J Exp Med. 1959 Jun 1;109(6):571-88. doi: 10.1084/jem.109.6.571.
4
Physiologic studies in renal osteodystrophy treated by subtotal parathyroidectomy.次全甲状旁腺切除治疗肾性骨营养不良的生理学研究
Am J Med. 1969 Jun;46(6):930-40. doi: 10.1016/0002-9343(69)90095-3.
5
The place of subtotal parathyroidectomy in the management of patients with chronic renal failure.次全甲状旁腺切除术在慢性肾衰竭患者治疗中的地位
Trans Am Soc Artif Intern Organs. 1968;14:376-84.
6
Prevention and reversal of progressive secondary hyperparathyroidism in patients maintained by hemodialysis.血液透析维持患者中进行性继发性甲状旁腺功能亢进的预防与逆转
Am J Med. 1974 Jun;56(6):827-32. doi: 10.1016/0002-9343(74)90811-0.
7
Transplantation of the parathyroid glands in dogs. Biochemical, histological, and radioimmunoassay proof of function.犬甲状旁腺移植。功能的生化、组织学及放射免疫测定证据。
Transplantation. 1973 Jan;15(1):179-82. doi: 10.1097/00007890-197301000-00027.
8
The hyperparathyroidism of renal failure: pathophysiology and treatment.肾衰竭的甲状旁腺功能亢进:病理生理学与治疗
Clin Endocrinol Metab. 1974 Jul;3(2):305-21. doi: 10.1016/s0300-595x(74)80012-5.
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The diagnosis and treatment of hyperparathyroidism after renal homotransplantation.同种异体肾移植术后甲状旁腺功能亢进的诊断与治疗
Surg Gynecol Obstet. 1973 Dec;137(6):997-1010.
10
Action of 1,25-dihydroxycholecalciferol, a potent, kidney-produced metabolite of vitamin D3, in uremic man.
N Engl J Med. 1972 Nov 2;287(18):891-5. doi: 10.1056/NEJM197211022871801.