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骨的生长与重塑。以鸡为对象的一项研究,特别涉及骨吸收机制。

Growth and remodeling of bone. An investigation in chicken with special reference to the mechanism of bone resorption.

作者信息

Olsson S E

出版信息

Acta Radiol Suppl. 1975;344:13-32.

PMID:60043
Abstract

Bone resorption was studied in chicken by means of histologic and microradiographic examination after intravital injections of three boneseeking fluorochromes. The fluorochromes were injected at intervals from 36 hours to 5 days, and the chicken were killed at 36 hours to 10 days after injection of the third fluorochrome. Signs of osteolysis, such as enlarged osteocyte lacunae surrounded by a metachromatic zone in toluidine blue stained sections, and confluence of osteocyte lacunae in microradiographs, were compared with the fluorochrome labelling pattern. There was no correlation between the histologic findings of osteolysis and the fluorochrome resorption pattern which indicated that existence of so-called bone flow. In the "haversian systems" at midshaft level, the color pattern remained unchanged till resorption took place from the endosteal side. Osteoclasia seemed to be the dominant mode of resorption. The conclusion was drawn that bone flow does not exist in the tibiae of chicken.

摘要

通过对三只注射骨亲和性荧光染料的鸡进行活体注射后,采用组织学和显微放射照相检查来研究骨吸收情况。荧光染料每隔36小时至5天注射一次,在注射第三种荧光染料后的36小时至10天处死鸡。在甲苯胺蓝染色切片中,将骨溶解的迹象,如被异染区包围的扩大的骨细胞陷窝,以及显微放射照片中骨细胞陷窝的融合,与荧光染料标记模式进行比较。骨溶解的组织学发现与表明存在所谓骨流的荧光染料吸收模式之间没有相关性。在骨干中部水平的“哈弗斯系统”中,颜色模式在从骨内膜侧发生吸收之前保持不变。破骨细胞似乎是主要的吸收方式。得出的结论是,鸡的胫骨中不存在骨流。

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