Homrowski S
Polim Med. 1977;7(2):91-7.
With the awareness of the possibility of drug-plastic interaction, before substitution of a plastic container for glass, steps should be taken to ensure safety. This process is fraught with difficulties because of the complexity of plastic materials and even wider range of drug substances offered for sale in a variety of dosage forms. The selection of an appropriate container for pharmaceutical should be preceded by adequate testing to recognize the properties of the packaging material, and the stability, safety, and compatibility of the preparation packed in it. The same care and control used in the manufacture of a drug product should be used for the plastic packaging system.
鉴于存在药物与塑料相互作用的可能性，在用塑料容器替代玻璃容器之前，应采取措施确保安全。由于塑料材料的复杂性以及以各种剂型出售的药物种类繁多，这个过程充满困难。在选择合适的药品包装容器之前，应进行充分的测试，以了解包装材料的特性以及包装在其中的制剂的稳定性、安全性和相容性。药品生产中所采用的同样的谨慎和控制措施也应用于塑料包装系统。
