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血液透析患者采用口服还是胃肠外铁剂治疗?

Oral or parenteral iron therapy in haemodialysis patients?

作者信息

Winney R J, Swainson C P, Parker A C, Bone J M, Robson J S

出版信息

Proc Eur Dial Transplant Assoc. 1977;14:184-91.

PMID:600955
Abstract

In 28 haemodialysis patients, in whom there was a high incidence of depleted marrow iron stores, a significant rise in Hb, and Hct, occasionally to a normal level, was achieved as effectively with oral as with i.v. iron supplements. There was a variable response to iron in individuals which could not be predicted from the initial iron status. No patient in whom marrow iron stores were reassessed after iron therapy developed increased marrow iron stores. Routine iron supplements are recommended in haemodialysis patients with regular monitoring of body iron stores.

摘要

在28例骨髓铁储备耗竭发生率较高的血液透析患者中,口服铁剂补充与静脉注射铁剂补充一样有效地使血红蛋白(Hb)和血细胞比容(Hct)显著升高,偶尔可升至正常水平。个体对铁的反应存在差异,无法根据初始铁状态预测。铁剂治疗后重新评估骨髓铁储备的患者中,没有出现骨髓铁储备增加的情况。建议对血液透析患者常规补充铁剂,并定期监测体内铁储备。

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