与脑组织发生反应的抗链球菌抗体。II. 超微结构研究。
Anti-streptococcal antibodies reacting with brain tissue. II. Utrastructural studies.
作者信息
Dorling J, Kingston D, Webb J A
出版信息
Br J Exp Pathol. 1976 Jun;57(3):255-65.
Abstract
The reaction of rabbit anti-Streptococcus pyogenes type 24 with mouse brain has been studied at the ultrastructural level using horseradish peroxidase labelled antiglobulin. It is shown that these antibodies, and by inference those found in Sydenham's chorea, react with the fibrous astrocyte. The cross-reacting antigen is the glial filament or a closely associated cytoplasmic constituent.
摘要
利用辣根过氧化物酶标记的抗球蛋白，在超微结构水平上研究了兔抗24型化脓性链球菌与小鼠脑的反应。结果表明，这些抗体以及由此推断在 Sydenham 舞蹈病中发现的抗体，与纤维性星形胶质细胞发生反应。交叉反应抗原是神经胶质丝或紧密相关的细胞质成分。
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