Syed A M, Feder B H, George F W
Radiol Clin (Basel). 1977;46(5):390-7.
(1) In all, 70 patients with carcinoma of the oral cavity and oropharynx have been treated utilizing one or more of several interstitial iridium-192 afterloading techniques. (2) After an 18-month minimum follow-up period, local control is still maintained in 9 of 10 patients with T1 and T2 lesions (UICC), in 17 of 22 patients with T3 lesions, and in 21 of 38 patients reirradiated for recurrent disease. The complication rate of 29% in the reirradiated patients, though high, is considered acceptable in these essentially hopeless cases. (3) This preliminary report is made to stimulate interest in the role of interstitial iridium-192 afterloading techniques. We feel they deserve evaluation in a controlled study of other head and neck cancer management techniques (including external irradiation, surgical resection and adjunctive chemotherapy).
（1）总体而言，70例口腔和口咽癌患者接受了一种或多种不同的铱-192组织间后装技术治疗。（2）经过至少18个月的随访期，10例T1和T2期（国际抗癌联盟）病变患者中有9例仍保持局部控制，22例T3期病变患者中有17例，38例因复发性疾病接受再照射的患者中有21例。再照射患者29%的并发症发生率虽高，但在这些基本无望的病例中被认为是可以接受的。（3）撰写本初步报告是为了激发人们对铱-192组织间后装技术作用的兴趣。我们认为，它们值得在一项关于其他头颈癌治疗技术（包括外照射、手术切除和辅助化疗）的对照研究中进行评估。
