Iwarson S
Scand J Infect Dis. 1977;9(4):297-9. doi: 10.3109/inf.1977.9.issue-4.08.
Long-term co-trimoxazole treatment (4-6 months) was tried in 7 chronic carriers of mainly Salmonella typhi and S. paratyphi B. No one had positive faecal cultures during treatment. Four faecal carriers were followed-up with regular cultures for at least 1 year after treatment and 3 of them remained negative. Long-term co-trimoxazole treatment seems to be well tolerated also in very old patients and may be worth trying also in cases where other antibiotics have failed.
对7名主要携带伤寒沙门氏菌和副伤寒乙杆菌的慢性带菌者尝试进行了为期4 - 6个月的复方新诺明治疗。治疗期间无人粪便培养呈阳性。4名粪便带菌者在治疗后接受了至少1年的定期培养随访，其中3人仍为阴性。长期复方新诺明治疗在高龄患者中似乎也耐受性良好，在其他抗生素治疗失败的情况下也可能值得一试。
