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尿素及其在腔棘鱼肝脏中的形成。

Urea and its formation in coelacanth liver.

作者信息

Brown G W, Brown S G

出版信息

Science. 1967 Feb 3;155(3762):570-3. doi: 10.1126/science.155.3762.570.

DOI:10.1126/science.155.3762.570
PMID:6015872
Abstract

Urea occurs in liver of the coelacanth Latimeria chalumnae to the extent of about 1.7 percent by weight. It was determined quantitatively by reaction with 1-phenyl-1,2-propanedione-2-oxime (Archibald reagent) and by measurement of ammonia released upon treatment with urease. Arginase and ornithine carbamoyltransferase, enzymes instrumental in the formation of urea in typical ureotelic vertebrates, occur in homogenates of coelacanth liver. Formed in part by the ornithine-urea cycle, urea may have an osmoregulatory function in the coelacanth as it has in elasmobranchs.

摘要

空棘鱼拉蒂迈鱼肝脏中尿素的含量约为体重的1.7%。通过与1-苯基-1,2-丙二酮-2-肟(阿奇博尔德试剂)反应并测定用脲酶处理后释放的氨进行定量测定。精氨酸酶和鸟氨酸氨甲酰基转移酶是典型排尿素脊椎动物中尿素形成过程中的关键酶,存在于空棘鱼肝脏的匀浆中。尿素部分由鸟氨酸-尿素循环形成,在空棘鱼中可能具有渗透调节功能,就像在板鳃亚纲鱼类中一样。

相似文献

1
Urea and its formation in coelacanth liver.尿素及其在腔棘鱼肝脏中的形成。
Science. 1967 Feb 3;155(3762):570-3. doi: 10.1126/science.155.3762.570.
2
Lungfish Neoceratodus forsteri: activities of ornithine-urea cycle and enzymes.肺鱼(澳洲肺鱼):鸟氨酸-尿素循环及酶的活性
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3
Evolution of urea synthesis in vertebrates: the piscine connection.脊椎动物尿素合成的演化:鱼类的联系
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Urea synthesis in the liver of the hypothyroid rat.甲状腺功能减退大鼠肝脏中的尿素合成
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[Study of ureogenesis in liver cirrhosis by determination of ornithine carbamoyl- transferase and arginase activity in hepatic biopsy specimens].
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Urea-cycle enzymes in liver disease.
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Ureogenesis in a freshwater teleost: an unusual sub-cellular localization of ornithine-urea cycle enzymes in the freshwater air-breathing teleost Heteropneustes fossilis.一种淡水硬骨鱼的尿素生成:淡水呼吸空气的硬骨鱼印度鲶鱼中鸟氨酸-尿素循环酶的异常亚细胞定位。
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Submitochondrial localization of arginase and other enzymes associated with urea synthesis and nitrogen metabolism, in liver of Squalus acanthias.棘鲨肝脏中精氨酸酶及其他与尿素合成和氮代谢相关酶的亚线粒体定位。
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Comp Biochem Physiol B Biochem Mol Biol. 2012 Apr;161(4):331-40. doi: 10.1016/j.cbpb.2011.12.006. Epub 2011 Dec 24.

引用本文的文献

1
THE ELEMENTARY COMPOSITION OF Latimeria chalumnae SMITH.矛尾鱼(拉蒂迈鱼)的基本组成成分
Proc Natl Acad Sci U S A. 1968 Jun;60(2):456-63. doi: 10.1073/pnas.60.2.456.
2
Special evolution of neurohypophysial hormones in cartilaginous fishes: asvatocin and phasvatocin, two oxytocin-like peptides isolated from the spotted dogfish (Scyliorhinus caniculus).软骨鱼类神经垂体激素的特殊进化:阿斯瓦托辛和法斯瓦托辛,从斑点角鲨(Scyliorhinus caniculus)中分离出的两种催产素样肽。
Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11266-70. doi: 10.1073/pnas.91.23.11266.
3
The anterior chamber of the coelacanth eye.
腔棘鱼眼睛的前房。
Br J Ophthalmol. 1968 May;52(5):415-8. doi: 10.1136/bjo.52.5.415.