金黄色葡萄球菌菌株间耐药因子的体内传播
In vivo transmission of drug resistance factors between strains of Staphylococcus aureus.
作者信息
Novick R P, Morse S I
出版信息
J Exp Med. 1967 Jan 1;125(1):45-59. doi: 10.1084/jem.125.1.45.
Abstract
- Multiply resistant strains of Staphylococcus aureus often harbor one or more extrachromosomal drug resistant factors as well as temperate prophages capable of mediating generalized transduction. 2. Spontaneous transduction occurs in mixed cultures of such staphylococcal strains, and the extrachromosomal resistance factors are involved more frequently than are chromosomal genes. 3. Spontaneous transduction of extrachromosomal determinants of erythromycin resistance and of linked penicillin-erythromycin resistance occurs in the kidneys of mice in which mixed infection has been induced.
摘要
- 耐多药金黄色葡萄球菌菌株通常携带一个或多个染色体外耐药因子以及能够介导普遍性转导的温和噬菌体。2. 自发转导发生在这类葡萄球菌菌株的混合培养物中，且染色体外耐药因子比染色体基因更频繁地参与其中。3. 在已诱导混合感染的小鼠肾脏中发生了红霉素耐药性的染色体外决定簇以及相关的青霉素 - 红霉素耐药性的自发转导。
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本文引用的文献
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