Dauphinee D, Langley G R
Can Med Assoc J. 1967 Feb 11;96(6):309-11.
Thirteen Canadians with a mild hypochromic anemia were found to have beta thalassemia trait. The families of these individuals had resided in Canada for two to five generations and, where known, had not emigrated from areas with a high incidence for the thalassemia gene. A Negro family with abnormal erythrocyte morphology was suspected to be carrying the thalassemia gene although the hemoglobin A(2) concentration was normal and abnormal minor components were not detected. Thalassemia trait has been detected in practically every ethnic group, and its sporadic occurrence among Canadians without Mediterranean ancestry can be expected.
13名患有轻度低色素性贫血的加拿大人被发现患有β地中海贫血特征。这些人的家族已在加拿大居住了两到五代，据了解，他们并未从地中海贫血基因高发地区移民而来。一个红细胞形态异常的黑人家庭被怀疑携带地中海贫血基因，尽管其血红蛋白A2浓度正常，且未检测到异常的次要成分。几乎在每个种族群体中都检测到了地中海贫血特征，因此可以预期在没有地中海血统的加拿大人中会偶尔出现这种情况。
