Harwood-Nash D C, Lansdown E L
Can Med Assoc J. 1967 Feb 4;96(5):245-56.
The urea washout (UWT) modification of the intravenous pyelogram was used to study 146 hypertensive patients in order to detect the presence of significant renovascular abnormalities. A positive result was obtained in 55 patients and direct confirmation of main renal artery stenoses by selective renal arteriography was obtained in 26. Bilateral abnormalities were confirmed in seven of the 26 patients. No false-negative results were encountered. The usefulness of this test as a comprehensive screening test is outlined. It demonstrated a high degree of accuracy in the diagnosis of significant unilateral or bilateral main renal artery stenosis in addition to the detection of diffuse intrarenal arteriolar disease. It was of value in the postoperative assessment of operative repair of main renal artery defects. The urea washout test embodies both an anatomical and a physiological approach in the roentgen diagnosis of curable renovascular hypertension. The altered physiology resulting from significant main renal artery stenosis makes possible the use of the urea washout intravenous pyelogram. The value of other forms of intravenous pyelography is described.
采用静脉肾盂造影的尿素清除率（UWT）改良法对146例高血压患者进行研究，以检测是否存在明显的肾血管异常。55例患者结果呈阳性，26例经选择性肾动脉造影直接证实存在主要肾动脉狭窄。26例患者中有7例证实为双侧异常。未出现假阴性结果。概述了该检查作为综合筛查试验的实用性。除了能检测弥漫性肾内小动脉疾病外，它在诊断明显的单侧或双侧主要肾动脉狭窄方面显示出高度准确性。它对主要肾动脉缺损手术修复的术后评估具有价值。尿素清除率试验在可治愈的肾血管性高血压的X线诊断中体现了解剖学和生理学方法。主要肾动脉明显狭窄导致的生理改变使得尿素清除率静脉肾盂造影成为可能。还描述了其他形式静脉肾盂造影的价值。
