Geokas M C, McKenna R D
Can Med Assoc J. 1967 Feb 18;96(7):411-7.
Although the mechanism for its development is not well understood, iron-deficiency anemia is a well-recognized consequence of partial gastrectomy. The reported incidence varies considerably, depending upon the criteria used to define anemia, and other factors. Rapid emptying of the gastric remnant, intestinal "hurry", and borderline dietary-iron intake, with or without concomitant blood loss, produce malabsorption of some forms of iron that appears to be responsible for development of the deficiency. The diagnosis rests on hematological findings in the peripheral blood, the evaluation of iron stores, epithelial changes, and the response to adequate treatment. Oral iron therapy can be both effective and inexpensive and should form the mainstay of treatment.
尽管缺铁性贫血的发病机制尚未完全明确,但它是部分胃切除术后公认的后果。报道的发病率差异很大,这取决于用于定义贫血的标准以及其他因素。胃残余物快速排空、肠道“蠕动过快”以及边缘性膳食铁摄入,无论有无伴随失血,都会导致某些形式的铁吸收不良,这似乎是导致缺铁的原因。诊断基于外周血的血液学检查结果、铁储存评估、上皮变化以及对充分治疗的反应。口服铁剂治疗既有效又便宜,应成为治疗的主要手段。