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胃部分切除术后缺铁性贫血

Iron-deficiency anemia after partial gastrectomy.

作者信息

Geokas M C, McKenna R D

出版信息

Can Med Assoc J. 1967 Feb 18;96(7):411-7.

PMID:6019057
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1935982/
Abstract

Although the mechanism for its development is not well understood, iron-deficiency anemia is a well-recognized consequence of partial gastrectomy. The reported incidence varies considerably, depending upon the criteria used to define anemia, and other factors. Rapid emptying of the gastric remnant, intestinal "hurry", and borderline dietary-iron intake, with or without concomitant blood loss, produce malabsorption of some forms of iron that appears to be responsible for development of the deficiency. The diagnosis rests on hematological findings in the peripheral blood, the evaluation of iron stores, epithelial changes, and the response to adequate treatment. Oral iron therapy can be both effective and inexpensive and should form the mainstay of treatment.

摘要

尽管缺铁性贫血的发病机制尚未完全明确,但它是部分胃切除术后公认的后果。报道的发病率差异很大,这取决于用于定义贫血的标准以及其他因素。胃残余物快速排空、肠道“蠕动过快”以及边缘性膳食铁摄入,无论有无伴随失血,都会导致某些形式的铁吸收不良,这似乎是导致缺铁的原因。诊断基于外周血的血液学检查结果、铁储存评估、上皮变化以及对充分治疗的反应。口服铁剂治疗既有效又便宜,应成为治疗的主要手段。

相似文献

1
Iron-deficiency anemia after partial gastrectomy.胃部分切除术后缺铁性贫血
Can Med Assoc J. 1967 Feb 18;96(7):411-7.
2
Iron deficiency following gastric resection.
Am J Gastroenterol. 1966 Feb;45(2):109-13.
3
The haematological management of patients following partial gastrectomy.胃部分切除术后患者的血液学管理
Br J Haematol. 1968 Nov;15(5):423-7. doi: 10.1111/j.1365-2141.1968.tb01561.x.
4
Comparison of absorption of 'slow-Fe' and ferrous sulphate tablets B.P. in patients following partial gastrectomy.
Scott Med J. 1972 Sep;17(9):314-5. doi: 10.1177/003693307201700906.
5
Iron absorption after total gastrectomy.全胃切除术后的铁吸收
Acta Chir Scand Suppl. 1965;343:118-21.
6
Microcytic anemia. Differential diagnosis and management of iron deficiency anemia.小细胞贫血。缺铁性贫血的鉴别诊断与管理
Med Clin North Am. 1992 May;76(3):549-66. doi: 10.1016/s0025-7125(16)30339-x.
7
Iron deficiency after partial gastrectomy.胃部分切除术后缺铁
Proc R Soc Med. 1970 Dec;63(12):1225-7. doi: 10.1177/003591577006301205.
8
[Causes and therapy of iron deficiency].
Haematol Blood Transfus. 1978;21:111-5.
9
[Iron-deficiency anemia: diagnosis and therapy].[缺铁性贫血:诊断与治疗]
Schweiz Med Wochenschr. 1992 Mar 28;122(13):461-5.
10
[Clinical aspects and therapy of iron deficiency].
Wien Med Wochenschr. 1984 Feb 29;134(3-4):74-81.

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Gastrointest Tumors. 2016 May;2(4):178-87. doi: 10.1159/000445188. Epub 2016 Apr 13.
2
Prevalence, severity, and evolution of postsurgical anemia after gastrectomy, and clinicopathological factors affecting its recovery.胃癌切除术后贫血的患病率、严重程度及演变情况,以及影响其恢复的临床病理因素。
J Korean Surg Soc. 2012 Feb;82(2):79-86. doi: 10.4174/jkss.2012.82.2.79. Epub 2012 Jan 27.
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Evaluation and treatment of iron deficiency anemia: a gastroenterological perspective.铁缺乏性贫血的评估与治疗:胃肠病学视角
Dig Dis Sci. 2010 Mar;55(3):548-59. doi: 10.1007/s10620-009-1108-6. Epub 2010 Jan 27.

本文引用的文献

1
The significance of Achlorhydria for the etiology of iron-deficiency anemia.胃酸缺乏在缺铁性贫血病因学中的意义。
Acta Med Scand. 1950;137(1):43-7. doi: 10.1111/j.0954-6820.1950.tb11364.x.
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Post-gastrectomy syndromes; a study in applied physiology.胃切除术后综合征;应用生理学研究
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Studies on iron absorption. I. The relationships between the rate of erythropoiesis, hypoxia and iron absorption.铁吸收的研究。I. 红细胞生成速率、缺氧与铁吸收之间的关系。
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Iron and vitamin B12 deficiency following subtotal gastrectomy. Report of a patient developing polycythemia vera following treatment.胃次全切除术后铁和维生素B12缺乏。1例患者治疗后发生真性红细胞增多症的报告。
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Prevalence of anaemia in the general population. A rural and an industrial area compared.普通人群中的贫血患病率。农村地区与工业区的比较。
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Peptic ulceration. Some haematological and metabolic consequences of gastric surgery.消化性溃疡。胃手术的一些血液学和代谢后果。
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Alimentary histology in the malabsorption syndrome following partial gastrectomy.胃部分切除术后吸收不良综合征的消化管组织学
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ROUTINE CHEMICAL TESTS OF THE STOOL FOR OCCULT BLOOD: AN EVALUATION.粪便潜血的常规化学检测:一项评估
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GASTRO-OESOPHAGEAL REFLUX AFTER PARTIAL GASTRECTOMY.胃部分切除术后的胃食管反流
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10
LATE POST-GASTRECTOMY SYNDROMES. OBSERVATIONS ON THE NATURE AND PATHOGENESIS OF ANAEMIA FOLLOWING PARTIAL GASTRECTOMY.胃切除术后晚期综合征。关于部分胃切除术后贫血的性质和发病机制的观察
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