固相肽合成装置。
Apparatus for solid-phase peptide synthesis.
作者信息
Khosla M C, Smeby R R, Bumpus F M
出版信息
Science. 1967 Apr 14;156(3772):253-4. doi: 10.1126/science.156.3772.253.
PMID:6021043
Abstract
The apparatus, designed for solid-phase peptide synthesis, consists of a round-bottom flask, rocked on a wrist-shaker, and fitted with a special dropping funnel and a fritted filter disc embedded within the flask. The dropping funnel is designed to wash down the polymer adhering to the neck of the flask. Solvents are removed through the fritted disc. Entire synthesis, and the removal of peptide from the polymer, are carried out without opening or removing the vessel from the shaker.
摘要
该仪器专为固相肽合成设计，由一个圆底烧瓶组成，该烧瓶在手腕振荡器上摇动，并配有一个特殊的滴液漏斗和一个嵌入烧瓶内的烧结滤盘。滴液漏斗用于冲洗粘附在烧瓶颈部的聚合物。溶剂通过烧结滤盘去除。整个合成过程以及从聚合物中去除肽的操作均在不打开或从振荡器上取下容器的情况下进行。
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