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气相色谱分析中的衍生化方法。在毒理学领域的应用(作者译)

[Derivatisation methods in gas chromatographic analysis. application in the toxicological field (author's transl)].

作者信息

Vycudilik W

出版信息

Z Rechtsmed. 1977 Nov 18;80(3):197-203. doi: 10.1007/BF02114616.

DOI:10.1007/BF02114616
PMID:602449
Abstract

Derivatisation methods are described, which can be used in gas chromatography of drugs in the forensic toxicological usage. Especially acetylation, silylation and methylation can be performed quite simply and fast. Several procedures for these reactions are compliled from the literature.

摘要

本文描述了衍生化方法,这些方法可用于法医毒理学中药物的气相色谱分析。特别是乙酰化、硅烷化和甲基化可以非常简单快速地进行。这些反应的几个程序是从文献中汇编而来的。

相似文献

1
[Derivatisation methods in gas chromatographic analysis. application in the toxicological field (author's transl)].气相色谱分析中的衍生化方法。在毒理学领域的应用(作者译)
Z Rechtsmed. 1977 Nov 18;80(3):197-203. doi: 10.1007/BF02114616.
2
[The significance of metabolites in toxicological analysis].[代谢物在毒理学分析中的意义]
Morphol Igazsagugyi Orv Sz. 1971 Jan;11(1):45-8.
3
Potentials of capillary gas chromatography in toxicology today.
Z Rechtsmed. 1984;93(4):237-50. doi: 10.1007/BF00198649.
4
The use of buffered celite columns in drug extraction techniques and their proposed application in forensic toxicology.
J Forensic Sci. 1977 Apr;22(2):376-82.
5
[Generic chemico-toxicological research in forensic toxicology. II. Considerations on the use of indices of retention and of delta I R in the methods of the gas-chromatographic test].[法医毒理学中的一般化学毒理学研究。II. 关于气相色谱测试方法中保留指数和ΔIR使用的考量]
Farmaco Prat. 1976 May;31(5):253-63.
6
Chromatography and forensic chemistry.色谱法与法医化学。
J Chromatogr Sci. 1974 Oct;12(10):529-34. doi: 10.1093/chromsci/12.10.529.
7
[Gas chromatographic analysis of some drugs (author's transl)].某些药物的气相色谱分析(作者译)
Rinsho Byori. 1978 Jan;26(1):44-7.
8
[Quantitative gas chromatographic determination of soporifics in forensic toxicology].
Beitr Gerichtl Med. 1969;26:219-26.
9
[General systematic chemico-toxicological research in forensic toxicology. I. Considerations on the gas-chromatographic test in the general chemico-toxicological research].[法医毒理学中的一般系统化学毒理学研究。I. 一般化学毒理学研究中气相色谱测试的考量]
Farmaco Prat. 1976 Apr;31(4):180-211.
10
[Trace analysis for drugs and poisons in human tissues].
Nihon Hoigaku Zasshi. 1992 Jun;46(3):212-24.

本文引用的文献

1
On-column methylation of barbituric acids.
Anal Chem. 1966 Dec;38(13):1948-9. doi: 10.1021/ac50155a076.
2
Gas chromatography of barbiturates, phenolic alkaloids, and xanthine bases: flash-heater methylation by means of trimethylanilinium hydroxide.
J Pharm Sci. 1969 Mar;58(3):370-1. doi: 10.1002/jps.2600580322.
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New approach to derivatization and gas-chromatographic analysis of barbiturates.
Clin Chem. 1974 Feb;20(2):192-4.
4
Selective liquid chromatographic isolation procedure for gas chromatographic-mass spectrometric analysis of 3-ketosteroids in biological materials.
J Chromatogr. 1976 Nov 3;126:705-16. doi: 10.1016/s0021-9673(01)84113-3.
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[The determination of barbiturates in biological matter].
Beitr Gerichtl Med. 1977;35:213-20.
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Steroid phosphorus compounds. V--Mass spectrometry of phosphinic esters of monohydroxy steroids.类固醇磷化合物。V——单羟基类固醇次膦酸酯的质谱分析。
Biomed Mass Spectrom. 1976 Apr;3(2):64-70. doi: 10.1002/bms.1200030205.