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Diffusion of glucose, insulin, inulin, and Evans blue protein into thoracic duct lymph of man.葡萄糖、胰岛素、菊粉和伊文思蓝蛋白在人体胸导管淋巴中的扩散。
J Clin Invest. 1967 Jun;46(6):903-10. doi: 10.1172/JCI105596.
2
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Concentration and transport of different sugars in the lymph of the thoracic duct and in blood of the portal vein in dogs after enteral and parenteral administration.犬经肠内和肠外给药后胸导管淋巴液和门静脉血液中不同糖类的浓度及转运情况。
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Lymphatic system changes in diabetes mellitus: role of insulin and hyperglycemia.糖尿病中的淋巴系统变化:胰岛素和高血糖的作用。
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SPECIFIC ACTIVITY OF INULIN-C14-OOH IN SERUM AND LYMPH OF NEPHRECTOMIZED DOG.肾切除狗血清和淋巴中菊粉 - C14 - OOH的比活性
Proc Soc Exp Biol Med. 1964 May;116:40-2. doi: 10.3181/00379727-116-29152.

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Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites.类别转换抗胰岛素抗体起源于多个淋巴部位的非常规抗原呈递。
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10
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本文引用的文献

1
Measurement of I-131-insulin and of insulin-like activity in cerebrospinal fluid of man.人体脑脊液中I-131-胰岛素及胰岛素样活性的测定。
Metabolism. 1962 Apr;11:416-20.
2
Measurement of small quantities of insulin-like activity using rat adipose tissue. I. A proposed procedure.利用大鼠脂肪组织测定少量胰岛素样活性。I. 一种推荐的方法。
J Clin Invest. 1960 Sep;39(9):1487-98. doi: 10.1172/JCI104168.
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STUDIES ON THE STATE OF INSULIN IN BLOOD: PROPERTIES OF CIRCULATING "FREE" AND "BOUND" INSULIN.血液中胰岛素状态的研究:循环“游离”和“结合”胰岛素的特性
Endocrinology. 1965 Apr;76:709-21. doi: 10.1210/endo-76-4-709.
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INSULIN RESPONSE TO GLUCOSE LOADING IN ACROMEGALY.肢端肥大症患者对葡萄糖负荷的胰岛素反应。
Lancet. 1964 Oct 10;2(7363):769-71. doi: 10.1016/s0140-6736(64)90556-2.
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INSULIN REGULATORY MECHANISMS AND DIABETES MELLITUS.胰岛素调节机制与糖尿病
Diabetes. 1964 May-Jun;13:230-40.
6
THE "TYPICAL" AND "ATYPICAL" FORMS OF SERUM INSULIN.血清胰岛素的“典型”和“非典型”形式。
Diabetes. 1963 Jul-Aug;12:339-48. doi: 10.2337/diab.12.4.339.
7
THE CONCENTRATION OF RADIOACTIVE IODINE IN THE THYROID LYMPH, THYROID VENOUS BLOOD AND PERIPHERAL BLOOD OF PRIMATES.灵长类动物甲状腺淋巴、甲状腺静脉血和外周血中放射性碘的浓度
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ANGIOTENSIN IN BLOOD AND LYMPH FOLLOWING REDUCTION IN RENAL ARTERIAL PERFUSION PRESSURE IN DOGS.犬肾动脉灌注压降低后血液和淋巴中的血管紧张素
Circ Res. 1963 Oct;13:336-45. doi: 10.1161/01.res.13.4.336.
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Estimation of Evans blue dye in blood plasma and its application to blood volume determination.血浆中伊文思蓝染料的测定及其在血容量测定中的应用。
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Transport of fatty acids.脂肪酸的转运
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葡萄糖、胰岛素、菊粉和伊文思蓝蛋白在人体胸导管淋巴中的扩散。

Diffusion of glucose, insulin, inulin, and Evans blue protein into thoracic duct lymph of man.

作者信息

Rasio E A, Hampers C L, Soeldner J S, Cahill G F

出版信息

J Clin Invest. 1967 Jun;46(6):903-10. doi: 10.1172/JCI105596.

DOI:10.1172/JCI105596
PMID:6026096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC297094/
Abstract

Immunoreactive insulin, like inulin, quickly equilibrates with interstitial fluid, as evidenced by recovery in thoracic duct lymph in man. Insulin-like activity not accounted for by immunoreactive insulin behaves as a large protein and is confined to the vascular compartment.

摘要

免疫反应性胰岛素,与菊粉一样,能迅速与细胞间液达到平衡,这在人体胸导管淋巴液中的回收情况中得到了证实。免疫反应性胰岛素无法解释的胰岛素样活性表现为一种大分子蛋白质,且局限于血管腔室。