Akerlund M, Andersson K E, Bengtsson L P, Laudanski T
Acta Obstet Gynecol Scand. 1977;56(4):381-5. doi: 10.3109/00016347709154997.
In two nonpregnant women with cranial diabetes insipidus, myometrial activity under different hormonal conditions was studied by intrauterine pressure recording. Recordings were performed when the women were under the influence of their regular treatment with desaminocys1-D-arg8-vasopressin (DDAVP), and when they had fully developed symptoms of their disease. Uterine activity was similar to that found in normal women under the same hormonal conditions, and generally did not change when symptoms of lack of vasopressin appeared. Both DDAVP (15-20 microgram), given intranasally, and lysin vasopressin (0.2 IU), given intravenously, stimulated uterine activity, particularly in late secretory menstrual phase. It is suggested that endogenous vasopressin is of minor importance for the induction of spontaneous uterine activity in nonpregnant women.
在两名患有颅咽管性尿崩症的未孕女性中，通过宫内压力记录研究了不同激素条件下的子宫肌层活动。记录分别在这些女性接受去氨基半胱氨酸1-D-精氨酸8-加压素（DDAVP）常规治疗时以及疾病症状完全显现时进行。子宫活动与在相同激素条件下的正常女性相似，并且在出现抗利尿激素缺乏症状时通常没有变化。经鼻给予的DDAVP（15 - 20微克）和静脉给予的赖氨酸加压素（0.2国际单位）均刺激子宫活动，尤其是在分泌期月经后期。提示内源性加压素对未孕女性自发性子宫活动的诱导作用较小。
