Ludwigsen E, Sørensen F H, Olsen S
Acta Pathol Microbiol Scand A. 1977 Nov;85(6):911-6. doi: 10.1111/j.1699-0463.1977.tb03908.x.
A quantitative investigation was performed of glomeruli in renal ibiopsies from patients with nephrotic syndrome or persisting proteinuria associated with normal light microscopic findings or slight changes not considered significant ("minimal change disease", lipoid nephrosis). The mesangial area was widened (+ 26 per cent, p less than 0.05) and there was an increase in the mean of the total number of cellular nuclei per glomerulus, the number of mesangial (+ 16 per cent) and edothelial nuclei (+ 23 per cent), but of these only endothelial hypercellularity was significant (p less than 0.025).
对肾病综合征患者或持续性蛋白尿患者的肾活检肾小球进行了定量研究，这些患者光镜检查结果正常或有不被认为具有显著意义的轻微改变（“微小病变病”，类脂性肾病）。系膜面积增宽（+26%，p<0.05），每个肾小球细胞核总数的平均值增加，系膜细胞核数量增加（+16%），内皮细胞核数量增加（+23%），但其中只有内皮细胞增多具有显著性（p<0.025）。
