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猫(Felis catus L.)常染色体磷酸葡萄糖酸脱氢酶多态性

Autosomal phosphogluconic dehydrogenase polymorphism in the cat (Felis catus L.).

作者信息

Thuline H C, Morrow A C, Norby D E, Motulsky A G

出版信息

Science. 1967 Jul 28;157(3787):431-2. doi: 10.1126/science.157.3787.431.

DOI:10.1126/science.157.3787.431
PMID:6028025
Abstract

Three patterns of 6-phosphogluconic dehydrogenase activity were obtained by starch-gel electrophoresis of blood from domestic cats. Genetic analysis indicates control of these patterns by a pair of alleles at an autosomal locus. Presence of three enzymatically active bands in heterozygotes and of single bands in homozygotes is compatible with at least a dimeric structure for the enzyme.

摘要

通过对家猫血液进行淀粉凝胶电泳,获得了6-磷酸葡萄糖酸脱氢酶活性的三种模式。遗传分析表明,这些模式受常染色体位点上一对等位基因的控制。杂合子中存在三条酶活性带,纯合子中存在单条带,这与该酶至少具有二聚体结构是相符的。

相似文献

1
Autosomal phosphogluconic dehydrogenase polymorphism in the cat (Felis catus L.).猫(Felis catus L.)常染色体磷酸葡萄糖酸脱氢酶多态性
Science. 1967 Jul 28;157(3787):431-2. doi: 10.1126/science.157.3787.431.
2
6-Phosphogluconic dehydrogenase polymorphism in the bobcat (Felis rufa Schreber).
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Rapid detection of 6-phosphogluconate dehydrogenase variants by electrophoresis on cellulose acetate gel.通过醋酸纤维素凝胶电泳快速检测6-磷酸葡萄糖酸脱氢酶变体
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Inherited quantitative variations of human phosphogluconate dehydrogenase.人类磷酸葡萄糖酸脱氢酶的遗传性数量变异
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[Purification and some properties of electrophoretic variants of 6-phosphogluconate dehydrogenase from rat erythrocytes].[大鼠红细胞6-磷酸葡萄糖酸脱氢酶电泳变体的纯化及某些性质]
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Human 6-phosphogluconate dehydrogenase. Purification of the erythrocyte enzyme and the influence of ions and NADPH on its activity.人6-磷酸葡萄糖酸脱氢酶。红细胞酶的纯化以及离子和NADPH对其活性的影响。
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[Determination of the phenotypes of several erythrocytic enzymes by cellulose acetate electrophoresis].[用醋酸纤维素电泳法测定几种红细胞酶的表型]
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Electrophoretic variants of human 6-phosphogluconate dehydrogenase: population and family studies and description of a new variant.人类6-磷酸葡萄糖酸脱氢酶的电泳变异体:群体与家系研究及一种新变异体的描述
Ann Hum Genet. 1967 May;30(4):355-61. doi: 10.1111/j.1469-1809.1967.tb00037.x.

引用本文的文献

1
Biochemical genetics of Fundulus heteroclitus (L.). III. Inheritance of isocitrate dehydrogenase (Idh-A and Idh-B), 6-phosphogluconate dehydrogenase (6-Pgdh-A), and serum esterase (Est-S) polymorphisms.异齿鳉(Fundulus heteroclitus,L.)的生化遗传学。III. 异柠檬酸脱氢酶(Idh-A和Idh-B)、6-磷酸葡萄糖酸脱氢酶(6-Pgdh-A)和血清酯酶(Est-S)多态性的遗传。
Biochem Genet. 1981 Aug;19(7-8):701-14. doi: 10.1007/BF00484003.
2
[On the formal genetics of isoenzymes, using 6-PGD (EC:1.1.1.44) as an example].
Humangenetik. 1969;7(1):1-4. doi: 10.1007/BF00278686.
3
[On the population genetics of 6-phosphogluconate dehydrogenase (EC:1.1.1.44): gene frequency in a sample from south-western Germany].[关于6-磷酸葡萄糖酸脱氢酶(EC:1.1.1.44)的群体遗传学:来自德国西南部一个样本中的基因频率]
Humangenetik. 1968;6(4):338-9.
4
Duplication of the autosomally inherited 6-phosphogluconate dehydrogenase gene locus in tetraploid species of cyprinid fish.
Biochem Genet. 1968 Sep;2(2):101-7. doi: 10.1007/BF01458709.
5
Synchronous activation of both parental alleles at the 6-PGD locus of Japanese quail embryos.日本鹌鹑胚胎6 -磷酸葡萄糖脱氢酶(6-PGD)基因座上双亲等位基因的同步激活。
Biochem Genet. 1968 Nov;2(3):197-204. doi: 10.1007/BF01474758.
6
[The genetics of 6-PGD (EC; 1.1.1.44) in various mammals. I. Studies on 6 species of Microtinae, Rodentia, Isoenzyme polymorphism and family studies in Microtus oeconomus and Microtus ochrogaster].
Humangenetik. 1970 Sep 17;10(2):151-7. doi: 10.1007/BF00295514.
7
De novo mutation-like events observed at the 6PGD locus of the Japanese quail, and the principle of polymorphism breeding more polymorphism.在日本鹌鹑的6-磷酸葡萄糖脱氢酶(6PGD)基因座观察到的从头突变样事件,以及多态性育种产生更多多态性的原理。
Biochem Genet. 1969 Oct;3(5):417-28. doi: 10.1007/BF00485603.
8
6-phosphogluconate dehydrogenase in the housefly, Musca domestica L.:evidence for inheritable 6PGD polymorphism.
Biochem Genet. 1979 Oct;17(9-10):855-65. doi: 10.1007/BF00504308.