Olivares J, Callao V, Montoya E
Science. 1967 Jul 21;157(3786):327-8. doi: 10.1126/science.157.3786.327.
The presence of toxohormone-like factor in autolysates of animal tissues was investigated. One could always isolate appreciable quantities of preparations having toxohormone activity. At the doses tested, no activity could be shown in preparations from nonautolyzed tissues. We suggest that autolysis phenomena may cause the presence of toxohormone in tumor-bearing organisms.
对动物组织自溶产物中类毒素激素样因子的存在情况进行了研究。总是能够分离出相当数量具有毒素激素活性的制剂。在所测试的剂量下,未自溶组织的制剂未显示出活性。我们认为自溶现象可能导致荷瘤生物体中存在毒素激素。