大鼠膈肌对某些甲基糖苷的通透性及其与单糖转运的关系。
Permeability of rat diaphragm muscle to some methyl glycosides and its relationship to monosaccharide transport.
作者信息
Wong H A, Randle P J
出版信息
Biochem J. 1967 Feb;102(2):618-22. doi: 10.1042/bj1020618.
Abstract
- Studies in vitro have shown that rat diaphragm muscle is freely permeable to alpha- and beta-methyl d-xylosides and beta-methyl l-arabinoside but not to alpha- or beta-methyl d-glucoside or alpha-methyl d-mannoside. 2. No competition for entry between methyl pentosides and d-xylose, l-arabinose, d-glucose or 3-O-methyl-d-glucose could be demonstrated and alpha-methyl xyloside entry was not inhibited by phlorrhizin. 3. It is concluded that the monosaccharide transport system is unlikely to contribute significantly to the entry of the methyl pentosides in this tissue.
摘要
- 体外研究表明，大鼠膈肌对α-和β-甲基-D-木糖苷以及β-甲基-L-阿拉伯糖苷可自由通透，但对α-或β-甲基-D-葡萄糖苷或α-甲基-D-甘露糖苷则不通透。2. 未证实甲基戊糖苷与D-木糖、L-阿拉伯糖、D-葡萄糖或3-O-甲基-D-葡萄糖之间存在进入竞争，并且根皮苷不抑制α-甲基木糖苷的进入。3. 得出的结论是，单糖转运系统不太可能对该组织中甲基戊糖苷的进入有显著贡献。
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