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[SKF 28175:一种新型抗抑郁药的初步研究]

[SKF 28,175: preliminary study of a new antidepressant].

作者信息

Denber H C, Wright J H, Russinovich N

出版信息

Ann Med Psychol (Paris). 1977 Apr;1(4):593-600.

PMID:603185
Abstract

This is a preliminary report concerning a new antidepressant, SKF 28,175 which is neither an IMAO nor does it have the usual tricyclic structure, retaining the CF 3 at the number two position on the ring. It was studied in 27 male and female patients. The drug was highly effective, within 4-7 days for the most part, as confirmed by statistical analysis of the Hamilton Rating Scale. There were relatively few side effects. Only one dosage per day, in the evening, was required.

摘要

这是一份关于新型抗抑郁药SKF 28,175的初步报告,它既不是单胺氧化酶抑制剂,也不具有常见的三环结构,在环上的2号位保留了三氟甲基。对27名男性和女性患者进行了研究。经汉密尔顿评定量表的统计分析证实,该药物在很大程度上在4至7天内具有高效性。副作用相对较少。每天只需在晚上服用一次剂量。

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