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[静脉注射葡萄糖、果糖、转化糖和山梨醇对马血浆中各种血液成分(单糖、胰岛素、乳酸、丙酮酸、游离脂肪酸以及谷氨酸草酰乙酸转氨酶)影响的研究]

[Studies on the effects of intravenous administration of glucose, fructose, invertose and sorbitol on various blood constituents of blood plasma (monosaccharides, insulin, lactate, pyruvate and free fatty acids as well as glutamate-oxaloacetate transaminase) in the horse].

作者信息

Kouider S, Kolb F E, Müller I, Pfüller C, Schneider J

出版信息

Arch Exp Veterinarmed. 1977;31(5):701-18.

PMID:603366
Abstract

Horses were examined for the behaviour of various blood constituents prior to and following infusions of solutions of glucose, fructose, invertose, and sorbitol. Infusion of 0.5 g/kg live weight glucose to six horses was followed by half-life variation between eleven and 23 minutes. Subsequent infusion of invertose to the same animals usually caused prolongation of glucose half-life. Half-life values were between 17 and 33 minutes for fructose and between 21 and 80 minutes for glucose. Infusion of 0.5 g/kg live weight fructose to two horses was followed by half-life values between 17 and 18 minutes, while the half-life values of sugar alcohol were 16, 16, 27, and 29 minutes in four horses who had received sorbitol. Sugar or sorbitol infusion was not followed by substantive change of lactate and pyruvate concentrations in the blood or free fatty acids in the blood plasma or GOT activity. The rise of insulin in the blood plasma was differentiated. Invertose and sorbitol solutions, consequently, can be recommended for application to horses.

摘要

对马匹输注葡萄糖、果糖、转化糖和山梨醇溶液前后的各种血液成分行为进行了检查。对6匹马输注每千克活体重0.5克的葡萄糖后,其半衰期在11至23分钟之间变化。随后对同一批动物输注转化糖通常会导致葡萄糖半衰期延长。果糖的半衰期值在17至33分钟之间,葡萄糖的半衰期值在21至80分钟之间。对2匹马输注每千克活体重0.5克的果糖后,其半衰期值在17至18分钟之间,而在接受山梨醇的4匹马中,糖醇的半衰期值分别为16、16、27和29分钟。输注糖或山梨醇后,血液中乳酸和丙酮酸的浓度、血浆中游离脂肪酸的浓度或谷草转氨酶(GOT)活性均无实质性变化。血浆中胰岛素的升高存在差异。因此,转化糖溶液和山梨醇溶液可推荐用于马匹。

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