双香豆素的生物合成
The biosynthesis of dicoumarol.
作者信息
Bellis D M, Spring M S, Stoker J R
出版信息
Biochem J. 1967 Apr;103(1):202-6. doi: 10.1042/bj1030202.
Abstract
Micro-organisms have been isolated that can utilize o-coumaric acid as a sole carbon source with the subsequent production of 4-hydroxycoumarin and dicoumarol. One of these organisms, Penicillium jenseni, has been used to examine the biosynthesis of dicoumarol. Certain thermophilic fungi have also been found that can convert o-coumaric acid into dicoumarol.
摘要
已分离出一些微生物，它们能够利用邻香豆酸作为唯一碳源，随后产生4-羟基香豆素和双香豆素。其中一种微生物，詹森青霉，已被用于研究双香豆素的生物合成。还发现某些嗜热真菌能够将邻香豆酸转化为双香豆素。
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本文引用的文献
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The Oxidation of Aromatic Compounds by Fluorescent Pseudomonads.荧光假单胞菌对芳香族化合物的氧化作用
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Utilization by soil fungi of p-hydroxybenzaidehyde, ferulic acid, syringaldehyde and vanillin.土壤真菌对对羟基苯甲醛、阿魏酸、丁香醛和香草醛的利用情况。
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Metabolism of coumarin and related compounds in cultures of Penicillium species.青霉属菌种培养物中香豆素及相关化合物的代谢
Nature. 1958 Sep 20;182(4638):806-7. doi: 10.1038/182806a0.
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Studies in detoxication. 72. The metabolism of coumarin and of o-coumaric acid.解毒研究。72. 香豆素和邻香豆酸的代谢
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