Holdaway M D, Kennedy J, Ashcroft T, Kay-Butler J J
Thorax. 1967 Jul;22(4):375-81. doi: 10.1136/thx.22.4.375.
Until 1960, 179 cases of infection with had been described in the world literature. Seventeen cases in children were reported by 1963. The organism is a common saprophyte in nature with probably a world-wide distribution. Infection can be primary but is more common in patients with underlying malignancy, auto-immune disease or preceding tuberculosis. Sulphonamides, particularly sulphadiazine, are the drugs of choice in treatment; the value of antibiotics is less clearly established. The indications for surgical treatment have not yet been defined. We record a further case of primary pulmonary nocardiosis in a 3-year-old child.
到1960年为止,世界文献中已描述了179例感染病例。到1963年报告了17例儿童感染病例。该病原体在自然界中是一种常见的腐生菌,可能分布于全球。感染可为原发性,但在患有潜在恶性肿瘤、自身免疫性疾病或既往有结核病的患者中更为常见。磺胺类药物,尤其是磺胺嘧啶,是治疗的首选药物;抗生素的价值尚不太明确。手术治疗的指征尚未确定。我们记录了一名3岁儿童原发性肺诺卡菌病的又一例病例。