Soares Diana, Reis-Melo Ana, Ferraz Catarina, Guedes Vaz Luisa
Department of Pediatrics, Centro Hospitalar Vila Nova de Gaia - Espinho EPE, Vila Nova de Gaia, Portugal.
Department of Pediatrics, Centro Hospitalar São João EPE, Porto, Portugal.
BMJ Case Rep. 2019 Jan 10;12(1):bcr-2018-227499. doi: 10.1136/bcr-2018-227499.
The authors report a case of a lung abscess caused by sp. in a previously healthy adolescent. A 17-year-old young man presented with tonsillitis that did not respond to β-lactamic antibiotic, dyspnoea and thoracic pain. The X-ray revealed a cavitation in the right pulmonary upper lobe. He was admitted and completed a 14-day empirical antimicrobial therapy for a pulmonar abscess, although no clinical recovery was observed. He then underwent pulmonary biopsy of the lesion and PCR analysis of the collected pulmonary tissue, which revealed the presence of This case emphasises the importance of considering nocardiosis in the differential diagnosis of a lung abscess, particularly if no response to empirical therapy is obtained.
作者报告了一例由 菌引起的肺脓肿病例，患者为一名此前健康的青少年。一名17岁青年出现对β-内酰胺类抗生素无反应的扁桃体炎、呼吸困难和胸痛。X线显示右肺上叶有空洞形成。他入院后接受了为期14天的针对肺脓肿的经验性抗菌治疗，但未见临床恢复。随后他接受了病变部位的肺活检以及对所采集肺组织的聚合酶链反应（PCR）分析，结果显示存在 菌。该病例强调了在肺脓肿的鉴别诊断中考虑诺卡菌病的重要性，尤其是在经验性治疗无效的情况下。
