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小鼠胚胎面部和内脏弓的发育：扫描电子显微镜研究

Facial and visceral arch development in the mouse embryo: a study by scanning electron microscopy.

作者信息

Tamarin A, Boyde A

出版信息

J Anat. 1977 Dec;124(Pt 3):563-80.

PMID:604328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1234654/
Abstract

The morphogenesis of the face and visceral arch region were studied by scanning electron microscopy in 63 mouse embryos between 8 and 13 days post coitum. The developmental stages were determined by reference to Theiler's (1971) scheme for the categorization of the normal stages of development. After the cervical fold is formed (stage 12) the mandibular primordium appears (stage 13) followed by the primordia of arches II and III (stage 14 with arch IV forming last (stage 15). Arches II, III and IV regress in reverse order, with no evidence that a cervical sinus pouch is formed. Placodes of the sensory ganglia from cranial nerves 7, 9 and 10 are formed in the first, second and third visceral grooves respectively. Formation of the external auditory meatus and its surrounding tubercles were also observed. Morphogenesis of the upper face is dominated by the midsagittal grove, which extends into the stomatodeum; and by the medial nasal, lateral nasal and maxillary processes. The temporal changes in shape and the interrelationships of the structures mentioned are described in detail.

摘要

通过扫描电子显微镜对63只交配后8至13天的小鼠胚胎的面部和内脏弓区域的形态发生进行了研究。发育阶段参照泰勒（1971年）的正常发育阶段分类方案确定。颈褶形成后（第12阶段），下颌原基出现（第13阶段），随后是第二和第三鳃弓原基（第14阶段，第四鳃弓最后形成（第15阶段））。第二、第三和第四鳃弓按相反顺序退化，没有证据表明形成了颈窦囊。分别在第一、第二和第三内脏沟中形成来自第7、9和10对脑神经的感觉神经节基板。还观察到外耳道及其周围结节的形成。上半面部的形态发生主要由延伸至口凹的矢状中沟以及内侧鼻突、外侧鼻突和上颌突主导。详细描述了上述结构的形状随时间的变化及其相互关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/ed1abee55a64/janat00364-0035-f.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/ed1abee55a64/janat00364-0035-f.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/2ed726663dec/janat00364-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/2f17f58dd3e0/janat00364-0029-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/91b8d9dcf54d/janat00364-0029-c.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/28a210e78449/janat00364-0031-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/6d88630273ab/janat00364-0031-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/dfe0f16916a8/janat00364-0031-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/71d2d15c2660/janat00364-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/ffa303e124ca/janat00364-0033-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/a73efb06c023/janat00364-0033-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/7dac2c0ee2e5/janat00364-0033-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/ec19b3e7ee81/janat00364-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/c631e60cd15f/janat00364-0035-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/30b0737c37ec/janat00364-0035-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/12e1cc113cc5/janat00364-0035-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/136d308d25f2/janat00364-0035-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a32b/1234654/ed1abee55a64/janat00364-0035-f.jpg

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