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[术后静脉血栓形成时纤维蛋白原降解产物E抗原的放射免疫测定。46例髋关节骨关节炎人工关节置换术的研究(作者译)]

[The radioimmunological assay of fibrinogen breakdown products with E antigen during postoperative venous thromboses. Study in 46 cases of arthroplasty for osteoarthrosis of the hip (author's transl)].

作者信息

Dechavanne M, Ville D, Clermont N, Pouillaude J M, Clermont A, Viala J J, de Mourgues G

出版信息

Nouv Presse Med. 1977 Nov 26;6(40):3721-4.

PMID:604924
Abstract

Twenty six patients (without thrombosis) had a normal 125I-fibrinogen test, among whom 15 had a normal phlebography; 18 patients (with thrombosis) had a positive 125I-fibrinogen test among whom 11 had a positive phlebography. There was a discrepancy between phlebography and 125I-fibrinogen test in 2 patients. In patients with thrombosis, there is a significantly increase of FgE levels for several days after the intervention. However the measurement of FgE is not a reliable test (4% of false positive and 38% of false negative); but it is always elevated in femoral and popliteal thrombosis.

摘要

26例(无血栓形成)患者125I - 纤维蛋白原试验正常,其中15例静脉造影正常;18例(有血栓形成)患者125I - 纤维蛋白原试验阳性,其中11例静脉造影阳性。2例患者静脉造影与125I - 纤维蛋白原试验结果存在差异。在有血栓形成的患者中,干预后数天FgE水平显著升高。然而,FgE的检测并非可靠的检查(假阳性率为4%,假阴性率为38%);但在股静脉和腘静脉血栓形成时其水平总是升高。

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