Reddy P R, Van Krey H P, Siegel P B
Poult Sci. 1977 Jul;56(4):1237-53. doi: 10.3382/ps.0561237.
The ultrastructure of adenohypophyseal gonadotrophs (GT-cells) from pullets of lines selected for high (HWS) and low (LWS) body weight was studied at various physiological ages. Increasing the photoperiod beyond 14 hours in a 24-hour cycle did not have a significant effect on the ultrastructure of GT-cells in either line. A qualitative analysis, based on the extent and complexity of the protein synthetic apparatus, suggested that the synthetic activity of gonadotrophs from HWS pullets was greater than that of LWS pullets at each of the ages studied. Although no significant differences were found in the frequency of pullets showing evidence of intracellular digestion of secretory products, the condition was more severe in the HWS than in the LWS females. Crinophagy tended to be positively correlated with cell activity in both lines. These observations suggest that selection for growth rate had a correlated effect on hypophyseal proteinaceous secretions. They also indicate that interactions between fluctuations in gonadotrophic cell activity, secreting mechanisms and neural thresholds for hormone action may be implicated in the manifestation of the erratic ovulation patterns.
对高体重（HWS）品系和低体重（LWS）品系小母鸡在不同生理年龄阶段腺垂体促性腺细胞（GT细胞）的超微结构进行了研究。在24小时周期内将光照时长增加至超过14小时，对两个品系GT细胞的超微结构均无显著影响。基于蛋白质合成装置的程度和复杂性进行的定性分析表明，在所研究的每个年龄阶段，HWS品系小母鸡促性腺细胞的合成活性均高于LWS品系。尽管在出现分泌产物细胞内消化迹象的小母鸡频率上未发现显著差异，但HWS品系的情况比LWS品系的雌性更为严重。在两个品系中，自噬性溶酶体消化往往与细胞活性呈正相关。这些观察结果表明，对生长速率的选择对垂体蛋白质分泌有相关影响。它们还表明，促性腺细胞活性波动、分泌机制和激素作用神经阈值之间的相互作用可能与不规律排卵模式的表现有关。
