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[Tolbutamide as a stimulator of somatotropin secretion from the hypophysis].

作者信息

Spanar E, Uhrín P, Levcík A, Záhradný V

出版信息

Z Gesamte Inn Med. 1977 Dec 15;32(24):694-5.

PMID:605639
Abstract

Our clinical experiments should point at the potential quality of tolbutamide as a stimulator of the secretion of the growth hormone. This could not be ascribed to the hypoglycaemic action of tolbutamide, because during the 240 minutes' time of the duration of the test, the glycaemic levels in the blood have been kept stabilised at the same levels as in fasting conditions before the application of tolbutamide, by a continuous intravenous drop of a 10% solution of glucose. The values of the growth hormone after application of tolbutamide raised two to fourfold in comparison to the initial value.

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