Kotelba-Witkowska B, Stachecki B, Chmiel J, Olszewska K
Acta Haematol Pol. 1977 Oct-Dec;8(4):289-301.
The relationship between the conditions of platelet preservation and their ultrastructure, metabolic activity, and the ability to carry out physiological functions was studied. It was found that storage of platelet concentrates at +4 degrees C for 72 hours reduced the number of platelets, changed their shape decreased the ATP level and the ability of release of adenine nucleotides in response to thrombin. The platelet at +22 degrees C for 72 hours preserved the initial number, normal ultrastructure, intact metabolic activity and the ability of participation in heamostasis processes.
研究了血小板保存条件与其超微结构、代谢活性及执行生理功能能力之间的关系。发现血小板浓缩物在4℃储存72小时会减少血小板数量,改变其形状,降低ATP水平以及对凝血酶刺激释放腺嘌呤核苷酸的能力。血小板在22℃储存72小时则能保持初始数量、正常的超微结构、完整的代谢活性以及参与止血过程的能力。