营养不良恢复过程中大鼠皮肤胶原蛋白的稳定性
Stability of rat skin collagen during recovery from under-nutrition.
作者信息
Etherington D J
出版信息
Biochem J. 1977 Dec 15;168(3):579-81. doi: 10.1042/bj1680579.
Abstract
The growth of young rats was arrested for 6 weeks from 48 h after receiving an injection of L-[5-3H]proline. The 3H in the hydroxyproline of the newly synthesized skin collagen remained steady during under-nutrition and did not decrease during the subsequent recovery period. It was concluded that in this animal model the renewed growth did not induce degradation of the pre-existing collagen fibres.
摘要
从注射L-[5-³H]脯氨酸48小时后起，幼鼠的生长停滞6周。在营养不足期间，新合成皮肤胶原蛋白中羟脯氨酸的³H保持稳定，且在随后的恢复期也未减少。得出的结论是，在这个动物模型中，重新生长并未诱导预先存在的胶原纤维降解。
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