感染性中性粒细胞减少患者可能的高剂量庆大霉素治疗。
Possible high dosage gentamycin therapy in infected neutropenic patients.
作者信息
Flandrois J P, Fière D, Martin C, Bonnet P
出版信息
Biomedicine. 1977 Dec;27(9-10):321-2.
PMID:606305
Abstract
Serum gentamycin levels have been studied in 23 neutropenic infected patients after high doses (62 mg/m2 and 72 mg/m2) of the drug, we observed: a higher gentamicin level than with an usual dosage, levels under the ototoxic 10/ml level, no renal failure, and, no patient ototoxicity.
摘要
对23名中性粒细胞减少的感染患者在使用高剂量（62毫克/平方米和72毫克/平方米）庆大霉素后进行了血清庆大霉素水平研究，我们观察到：庆大霉素水平高于常规剂量时的水平，低于耳毒性阈值10微克/毫升，无肾衰竭，且无患者出现耳毒性。
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