Boyle I T, Fogelman I, Boyce B, Thomson J E, Beastall G H, McIntosh W B, McLennan I
Clin Endocrinol (Oxf). 1977 Dec;7 Suppl:215s-222s. doi: 10.1111/j.1365-2265.1977.tb03384.x.
The surgical management of primary hyperparathyroidism with severe bone disease (and tertiary hyperparathyroidism) has frequently been complicated by severe and prolonged post-operative hypocalcaemia. In seven such cases a short-pre-operative course of 1alpha-hydroxyvitamin D3 has been found to abolish these adverse features virtually completely and even to diminish pre-operative symptoms where present. Exacerbation of hypercalcaemia has not occurred and this regimen is thus recommended as a routine measure.
