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免疫后小鼠脾脏中核苷酸代谢几种酶的比活性。

Specific activity of several enzymes of nucleotide metabolism in mouse spleen after immunization.

作者信息

Raska K, Cohen E P

出版信息

Clin Exp Immunol. 1967 Sep;2(5):559-64.

Abstract

The specific activity of uridine kinase and rate of UMP formation in the particle-free extract of mouse spleen increased within 8 hr after the intraperitoneal injection of SRBC. This heightened activity was found up to 72 hr and by 144 hr returned to or below control levels. The thymidine kinase activity increased up to 48 hr and then decreased to normal levels by 144 hr. Activities of both uridine kinase and thymidine kinase were additive after the simultaneous injection of SRBC and BGG.

摘要

小鼠脾脏无细胞提取物中尿苷激酶的比活性和UMP形成速率在腹腔注射SRBC后8小时内升高。这种增强的活性在72小时内都能检测到,到144小时时恢复到或低于对照水平。胸苷激酶活性在48小时内升高,然后在144小时时降至正常水平。同时注射SRBC和BGG后,尿苷激酶和胸苷激酶的活性呈相加作用。

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