Benn P, Chern C J, Bruns G, Craig I W, Croce C M
Cytogenet Cell Genet. 1977;19(5):273-80. doi: 10.1159/000130820.
In human fibroblast cultures derived from adults, clones of cells with a common chromosome rearrangement have been widely reported. Cells derived from one of these clones have been used in hybridization experiments using mouse cells to localize the genes for beta-glucuronidase and mitochondrial malate dehydrogenase on human chromosome 7. The results of this study indicate that the genes for these isozymes are located on the region pter leads to q22 of human chromosome 7.
在源自成年人的人类成纤维细胞培养物中,具有常见染色体重排的细胞克隆已被广泛报道。来自其中一个克隆的细胞已被用于与小鼠细胞进行杂交实验,以将β-葡萄糖醛酸酶和线粒体苹果酸脱氢酶的基因定位到人类第7号染色体上。这项研究的结果表明,这些同工酶的基因位于人类第7号染色体从pter到q22的区域。