Kosoković F, Vecerina S, Konić V
Laryngol Rhinol Otol (Stuttg). 1976 Feb;55(2):91-5.
The mechanical irritation alone or in combination with an inflammatory component and fragility of blood vessels plays the decisive role in the development of some vocal cord morphological changes. The duration of the mechanical irritation modifies the clinical picture. The plase of the strongest physiological mechanical irritation is the place of localization of the vocal cord morphological changes. The histological picture of different pathomorphological vocal cord changes is almost identical, this being the consequence of the specific structure of Reinke's subepithelial space. The treatment of all these morphological entities is surgical by means of microlaryngoscopy, except in cases of recent nodules which respond to conservative phoniatric therapy in the majority of cases.
单纯的机械性刺激，或与炎症成分及血管脆弱性相结合，在某些声带形态学改变的发生发展中起决定性作用。机械性刺激的持续时间会改变临床表现。最强生理性机械刺激的部位就是声带形态学改变的定位部位。不同病理形态学声带改变的组织学表现几乎相同，这是Reinke上皮下间隙特殊结构的结果。除了近期的小结节在大多数情况下对保守性发声治疗有反应外，所有这些形态学病变的治疗均通过显微喉镜手术进行。
