An hypothesis on the mechanism of action of 6-thioguanine.

Suppr

超能文献

作者信息

Miech R P, Parks R E, Anderson J H, Sartorelli A C

出版信息

Biochem Pharmacol. 1967 Nov;16(11):2222-7. doi: 10.1016/0006-2952(67)90022-6.

DOI:10.1016/0006-2952(67)90022-6

PMID:6076613

Abstract

摘要

相似文献

An hypothesis on the mechanism of action of 6-thioguanine.

Biochem Pharmacol. 1967 Nov;16(11):2222-7. doi: 10.1016/0006-2952(67)90022-6.

Adenosine triphosphate-guanosine 5'-phosphate phosphotransferase. II. Inhibition by 6-thioguanosine 5'-phosphate of the enzyme isolated from hog brain and sarcoma 180 ascites cells.三磷酸腺苷-5'-磷酸鸟苷磷酸转移酶。II. 5'-磷酸-6-硫代鸟苷对从猪脑和肉瘤180腹水细胞中分离出的该酶的抑制作用。

Mol Pharmacol. 1969 Jan;5(1):30-7.

Biochemical mechanisms for the synergism between 6-thioguanine and 6-(methylmercapto)purine ribonucleoside in sarcoma 180 cells.6-硫鸟嘌呤与6-（甲硫基）嘌呤核糖核苷在肉瘤180细胞中协同作用的生化机制。

Cancer Res. 1972 Oct;32(10):2034-41.

Adenosine triphosphate-guanosine 5'-phosphate phosphotransferase. IV. Isozymes in human erythrocytes and Sarcoma 180 ascites cells.

Mol Pharmacol. 1972 Mar;8(2):128-38.

Enzymic flux rates within the mononucleotides of the mouse liver.小鼠肝脏单核苷酸内的酶促通量率。

Eur J Biochem. 1969 Dec;11(3):549-53. doi: 10.1111/j.1432-1033.1969.tb00807.x.

THE INTERCONVERSION OF PURINES BY TUMORS AND THE ACTION OF ANTI-PURINES.肿瘤中嘌呤的相互转化及抗嘌呤的作用

Acta Unio Int Contra Cancrum. 1964;20:115-7.

Biochemical mechanism of resistance of cultured sarcoma 180 cells to 6-thioguanine.培养的肉瘤180细胞对6-硫鸟嘌呤耐药的生化机制。

Biochem Pharmacol. 1981 Nov 15;30(22):3109-14. doi: 10.1016/0006-2952(81)90501-3.

Inhibition of inosinic acid dehydrogenase of sarcoma 180 ascites cells by nucleotides and their analogs.核苷酸及其类似物对肉瘤180腹水癌细胞肌苷酸脱氢酶的抑制作用。

Biochem Pharmacol. 1969 Oct;18(10):2747-57. doi: 10.1016/0006-2952(69)90182-8.

Rabbit liver guanine deaminase. Chemical, physical, and kinetic properties.兔肝鸟嘌呤脱氨酶。化学、物理及动力学性质。

J Biol Chem. 1974 Jun 25;249(12):3862-6.

Conversion of 6-thioguanine to the nucleoside level by purine nucleoside phosphorylase of sarcoma 180 and sarcoma 180/TG ascites cells.肉瘤180和肉瘤180/TG腹水细胞的嘌呤核苷磷酸化酶将6-硫鸟嘌呤转化为核苷水平。

Cancer Res. 1981 Mar;41(3):1086-90.

引用本文的文献

An enumerative assay of purine analogue resistant lymphocytes in women heterozygous for the Lesch-Nyhan Mutation.对莱施-奈恩突变杂合子女性中嘌呤类似物抗性淋巴细胞的计数分析。

Biochem Genet. 1980 Jun;18(5-6):529-47. doi: 10.1007/BF00484400.

Differences between rat liver epithelial cells and fibroblast cells in sensitivity to 8-azaguanine.大鼠肝上皮细胞与成纤维细胞对8-氮杂鸟嘌呤敏感性的差异。

In Vitro. 1980 Aug;16(8):661-8. doi: 10.1007/BF02619195.

Purines as 'hyper-repressors' of glucose transport. A role for phosphoribosyl diphosphate.嘌呤作为葡萄糖转运的“超抑制剂”。磷酸核糖二磷酸的作用。

Biochem J. 1983 Jul 15;214(1):133-44. doi: 10.1042/bj2140133.

6-thioguanine: antimitotic effect on human lymphocytes in vitro prevented by adenine.6-硫鸟嘌呤：腺嘌呤可在体外阻止其对人淋巴细胞的抗有丝分裂作用。

Br J Cancer. 1971 Mar;25(1):106-8. doi: 10.1038/bjc.1971.15.

Toxicity of 6-thioguanine and 8-azaguanine to non-dividing liver cell cultures.6-硫鸟嘌呤和8-氮鸟嘌呤对非分裂肝细胞培养物的毒性

Cell Biol Toxicol. 1985 Jan;1(2):67-73. doi: 10.1007/BF00717792.

The 1985 Walter Hubert lecture. Malignant cell differentiation as a potential therapeutic approach.1985年沃尔特·休伯特讲座。恶性细胞分化作为一种潜在的治疗方法。

Br J Cancer. 1985 Sep;52(3):293-302. doi: 10.1038/bjc.1985.193.

Phase II trial of 5 day continuous intravenous infusion of 6-thioguanine in patients with recurrent and metastatic squamous cell carcinoma of the head and neck.头颈部复发和转移性鳞状细胞癌患者接受5天连续静脉输注6-硫鸟嘌呤的II期试验。

Invest New Drugs. 1992 Jul;10(2):89-91. doi: 10.1007/BF00873122.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验