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[不同跨壁压力下大鼠颈动脉的长度-力关系。实验与模型(作者译)]

[Length-force relation of rat-carotid artery at different transmural pression. Experiments and models (author's transl)].

作者信息

Weizsäcker H W, Pascale K

出版信息

Basic Res Cardiol. 1977 Nov-Dec;72(6):619-27. doi: 10.1007/BF01907042.

Abstract

The relation between force and extension in longitudinal direction as a function of the internal pressure was examined in isolated carotid arteries of rats using a device for testing the stress-strain relation of fibers (Vibrodyn). In the region of small longitudinal extensions the longitudinal force is decreased by raising the internal pressure. The longitudinal force is increased as a function of the internal pressure in the region of high longitudinal extensions. This behaviour can be explained by a model of the arterial wall which takes into account the spiral structure of the fibers. We could find a good qualitative agreement between this model and our experiments. It can be concluded that the histological structure plays an important role in determining the elastic behaviour of the arterial wall.

摘要

使用一种用于测试纤维应力-应变关系的装置(振动测力计),在大鼠离体颈动脉中研究了纵向力与纵向伸长之间的关系作为内压的函数。在纵向伸长较小的区域,纵向力会随着内压升高而降低。在纵向伸长较大的区域,纵向力会随着内压升高而增加。这种行为可以通过一个考虑了纤维螺旋结构的动脉壁模型来解释。我们发现该模型与我们的实验在定性上有很好的一致性。可以得出结论,组织学结构在决定动脉壁的弹性行为中起着重要作用。

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