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[肝门部癌的外科治疗]

[Surgical treatment of hilus cancers].

作者信息

Bismuth H, Castaing D

出版信息

Acta Chir Belg. 1984 Sep-Oct;84(5):307-11.

PMID:6083682
Abstract

Carcinomas of the hilus are malignancies which obstruct the upper part of the bile duct, including the Klatskin tumour but also neighbouring carcinomas invading the hilus and obstructing the biliary tract at this level. The aim of the treatment is to remove the tumour but in our experience, this radical treatment can be accomplished in only 10% of the carcinomas of the hilus. Therefore, the treatment is in the majority of the cases only palliative and the technique the authors used is the intrahepatic cholangio-anastomosis between the duct of Segment III and a Roux-en-Y jejunal loop by the approach of the intrahepatic duct in the Round Ligament fissura. In 61 cases of intrahepatic cholangioanastomoses, performed for the majority according this technique, the mortality was 6.5% and the mean survival 10.3 +/- 2.7 months with extremes of 2 to 72 months. The large variability of this survival is not in relation with the quality of the anastomosis but with the extent and the evolutivity of the carcinoma. Among the surgical and non-surgical palliative treatments of carcinomas of the hilus, the intrahepatic cholangio-anastomosis is the procedure which gives the best comfort and less iatrogenic complications.

摘要

肝门部癌是阻塞胆管上部的恶性肿瘤,包括肝门部胆管癌(Klatskin瘤)以及侵犯肝门并在此水平阻塞胆道的邻近癌。治疗目的是切除肿瘤,但根据我们的经验,仅10%的肝门部癌能完成这种根治性治疗。因此,在大多数情况下,治疗仅为姑息性,作者采用的技术是通过圆韧带裂的肝内胆管入路,在Ⅲ段胆管与Roux-en-Y空肠袢之间进行肝内胆管吻合术。在按照该技术进行的61例肝内胆管吻合术中,多数患者的死亡率为6.5%,平均生存期为10.3±2.7个月,最短2个月,最长72个月。这种生存期的巨大差异与吻合质量无关,而是与癌的范围和进展情况有关。在肝门部癌的手术和非手术姑息治疗中,肝内胆管吻合术是能提供最佳舒适度且医源性并发症较少的手术。

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