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[垂体后叶素性高血压时眼组织的生物电、生化及组织形态学变化以及氨茶碱和罂粟碱的应用]

[Bioelectrical, biochemical and histomorphological changes in the ocular tissues in pituitrin hypertension and the use of euphylline and papaverine].

作者信息

Strelkova N F, Chernov I P

出版信息

Farmakol Toksikol. 1984 Nov-Dec;47(6):53-6.

PMID:6083880
Abstract

Experimental study on rabbits of bioelectric and biochemical characteristics of eye tissues during pituitrin hypertension and application of euphylline and papaverine as well as comparison of the data obtained indicate that during pituitrin hypertension, transtissue potential difference and density of short-circuit current in the lens are considerably increased whereas the level of tissue respiration in the eye is reduced. Administration of euphylline or papaverine during pituitrin hypertension aggravates hemodynamic disorders in eye tissues, deteriorates the bioelectric and biochemical characteristics in both hypertensive and control animals.

摘要

对兔进行的实验研究,观察垂体后叶素性高血压期间眼组织的生物电和生化特性,以及应用氨茶碱和罂粟碱,并对所得数据进行比较,结果表明,在垂体后叶素性高血压期间,晶状体中的跨组织电位差和短路电流密度显著增加,而眼组织呼吸水平降低。在垂体后叶素性高血压期间给予氨茶碱或罂粟碱会加重眼组织的血液动力学紊乱,使高血压动物和对照动物的生物电和生化特性恶化。

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