Wendt P, Fritsch A, Schulz F, Wunderlich G, Blümel G
Hepatogastroenterology. 1984 Dec;31(6):277-81.
Examination of the peritoneal exudates of 12 patients with acute pancreatitis revealed high activities of pancreatic lipase and amylase. The immunologic levels of the plasma-derived inhibitors alpha 1-antitrypsin, antithrombin III and alpha 2-macroglobulin in the peritoneal exudates were not markedly different from those of the plasma. However, the inhibitory capacity of alpha 2-macroglobulin, the main inhibitor of human pancreatic trypsin in the exudate, was almost completely depleted when measured by an enzymatic method. Furthermore, spontaneous fibrinolysis occurred in 6 out of 13 exudates applied to plasminogen-free fibrin plates, indicating the presence of free proteinase. This fibrinolytic activity might be inhibited by exogenous alpha 2-macroglobulin or aprotinin (Trasylol, Bayer AG).
对12例急性胰腺炎患者的腹腔渗出液进行检查，发现其中胰脂肪酶和淀粉酶的活性很高。腹腔渗出液中血浆源性抑制剂α1-抗胰蛋白酶、抗凝血酶III和α2-巨球蛋白的免疫水平与血浆中的水平无明显差异。然而，用酶法测定时，渗出液中人类胰蛋白酶的主要抑制剂α2-巨球蛋白的抑制能力几乎完全耗尽。此外，在应用于无纤溶酶原纤维蛋白平板的13份渗出液中，有6份发生了自发纤维蛋白溶解，表明存在游离蛋白酶。这种纤维蛋白溶解活性可能会被外源性α2-巨球蛋白或抑肽酶（特血乐，拜耳公司）抑制。
