Antigenic structure of human chorionic somatomammotropin: four epitopes revealed by monoclonal antibodies.
作者信息
Mariani M, Cianfriglia M, Neri P, Lafata M, Antoni G
出版信息
J Immunol Methods. 1984 Dec 31;75(2):395-401. doi: 10.1016/0022-1759(84)90123-6.
PMID:6084032
Abstract
The characterization of epitope specificity of a panel of 15 monoclonal antibodies against human chorionic somatomammotropin (hCS), previously prepared in our laboratory, allowed us to distinguish 4 antigenic determinants on the hCS molecule. Experiments were carried out with competition and sandwich assays. The results allowed us to divide our MAbs into 4 groups, recognizing 4 different epitopes, and to select 4 MAbs each distinguishing a different epitope in order to pursue further studies on the antigenic structure of hCS.
摘要
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