Sobel B E
J Cardiovasc Pharmacol. 1984;6 Suppl 6:S910-3.
The therapeutic history of thrombolysis in coronary heart disease is relatively recent, but is now stimulating rapidly increasing interest. Studies of the evolution of acute coronary thrombosis demonstrate the urgent necessity to commence thrombolysis treatment at the earliest possible moment. The development of newer specific thrombolytic agents with low toxicity, without antigenicity, and available for rapid parenteral administration holds much promise for the treatment of acute myocardial infarction in the future.
冠心病溶栓治疗的历史相对较短,但目前正迅速激发越来越多的关注。对急性冠状动脉血栓形成演变的研究表明,尽早开始溶栓治疗迫在眉睫。开发毒性低、无抗原性且可快速胃肠外给药的新型特异性溶栓剂,对未来急性心肌梗死的治疗大有希望。