Dequeker J, Goddeeris T, De Roo M, Boeckx L
Eur J Nucl Med. 1977 Dec 30;2(4):269-71. doi: 10.1007/BF00252576.
The uptake of 99mTc in the small joints of the hand has been compared to various other mesures of inflammation in 22 patients with rheumatoid arthritis. The 99mTc uptake in the finger joints can reflect both disease activity at a given time and change in activity over a period of time. The place of Tc uptake amongst other measures of inflammation, from the point of view of the 'relative efficiency' of the assessment method, is rather inferior. In evaluating the effect of antiphlogistic drugs on local inflammation, techneticum uptake may, however, prove more discriminating than grip-strength or the number of painful joints, since the latter measures depend largely on the degree of destruction.
对22例类风湿性关节炎患者手部小关节中99m锝的摄取情况与其他多种炎症指标进行了比较。手指关节中99m锝的摄取既能反映特定时间的疾病活动情况,也能反映一段时间内活动情况的变化。从评估方法的“相对效率”角度来看,锝摄取在其他炎症指标中的地位相对较低。然而,在评估抗炎药物对局部炎症的效果时,锝摄取可能比握力或疼痛关节数量更具区分性,因为后两者在很大程度上取决于破坏程度。